Genomic & Biopharma News

Celgene-backed Aadi in the driving seat with $23M Series A round
Celgene-backed Aadi in the driving seat with $23M Series A round badams Mon, 05/08/2017 - 08:28
Fierce Biotech, 2017-05-08 12:28:46

The long noncoding RNA SPRIGHTLY acts as an intranuclear organizing hub for pre-mRNA molecules
Molecular mechanisms by which long noncoding RNA (lncRNA) molecules may influence cancerous condition are poorly understood. The aberrant expression of SPRIGHTLY lncRNA, encoded within the drosophila gene homolog Sprouty-4 intron, is correlated with a variety of cancers, including human melanomas. A team led by researchers at the Sanford Burnham Prebys Medical Discovery Institute demonstrate by ...
lncRNA Research and Industry News, 2017-05-08 12:26:34

Drug used to treat bipolar disorder may help prevent brain cell damage in TBI patients
A drug used to treat bipolar disorder and other forms of depression may help to preserve brain function and prevent nerve cells from dying in people with a traumatic brain injury, according to a new Rutgers University study.
News Medical Life Sciences, 2017-05-08 12:12:38

Regeneron pens Inovio I-O combo cocktail pact for aggressive brain tumors
Regeneron pens Inovio I-O combo cocktail pact for aggressive brain tumors badams Mon, 05/08/2017 - 08:03
Fierce Biotech, 2017-05-08 12:03:34

Exosomes and the Prion Protein
Exosomes are involved in the progression of neurodegenerative diseases. The cellular prion protein (PrPC) is highly expressed on exosomes. In neurodegenerative diseases, PrPC has at least two functions: It is the substrate for the generation of pathological prion protein (PrPSc), a key player in the pathophysiology of prion diseases. On the other hand, it binds ...
Exosome RNA Research & Industry News, 2017-05-08 12:02:41

Power analysis for RNA-Seq differential expression studies
Sample size calculation and power estimation are essential components of experimental designs in biomedical research. It is very challenging to estimate power for RNA-Seq differential expression under complex experimental designs. Moreover, the dependency among genes should be taken into account in order to obtain accurate results. Researchers from The Ohio State University propose a simulation based ...
Transcriptome Research & Industry News, 2017-05-08 11:48:36

Machine learning algorithm can help predict progression of age-related macular degeneration
Scientists have demonstrated that a machine learning algorithm, using images of patients' retinas obtained over time, can predict the critical moment when early or intermediate age-related macular degeneration (AMD) will progress into severe AMD.
News Medical Life Sciences, 2017-05-08 11:35:42

Gestational exposure to marijuana smoke may have lasting effects on the retina
Scientists have shown for the first time that gestational exposure to marijuana smoke in animals affects the development of the eye and these alterations seem to progress with age.
News Medical Life Sciences, 2017-05-08 11:31:51

Celgene, Regeneron and Vertex execs, NIH chief head to White House as threat of Trump funding cuts looms
Celgene, Regeneron and Vertex execs, NIH chief head to White House as threat of Trump funding cuts looms nptaylor Mon, 05/08/2017 - 07:30
Fierce Biotech, 2017-05-08 11:30:20