Genomic & Biopharma News

Scientists achieve closest view of working nerve synapses using custom-built microscope
The brain hosts an extraordinarily complex network of interconnected nerve cells that are constantly exchanging electrical and chemical signals at speeds difficult to comprehend.
News Medical Life Sciences, 2017-03-24 12:33:56

New analysis reveals high rate of colon cancer screening among dialysis patients
A new analysis reveals a relatively high rate of colon cancer screening among US patients on dialysis, even though they rarely stand to benefit from such screening. The findings appear in an upcoming issue of the Journal of the American Society of Nephrology.
News Medical Life Sciences, 2017-03-24 12:17:07

Achieving the Promise of Therapeutic Extracellular Vesicles
Extracellular vesicles (EVs) represent a class of cell secreted organelles which naturally contain biomolecular cargo such as miRNA, mRNA and proteins. EVs mediate intercellular communication, enabling the transfer of functional nucleic acids from the cell of origin to the recipient cells. In addition, EVs make an attractive delivery vehicle for therapeutics owing to their increased ...
Exosome RNA Research & Industry News, 2017-03-24 12:15:32

Seven LncRNA-mRNA based risk score predicts the survival of head and neck squamous cell carcinoma
Dysregulation of mRNAs and long non-coding RNAs (lncRNAs) is one of the most important features of carcinogenesis and cancer development. However, studies integrating the expression of mRNAs and lncRNAs to predict the survival of head and neck squamous cell carcinoma (HNSC) are still limited, hitherto. In current work, researchers at the Zhejiang University School of ...
lncRNA Research and Industry News, 2017-03-24 12:09:48

Should Healthy People Have Their Exomes Sequenced?
With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.
The Scientist, 2017-03-24 12:00:00

Xenon acne drug misses efficacy endpoints in phase 2
Xenon acne drug misses efficacy endpoints in phase 2 nptaylor Fri, 03/24/2017 - 07:47
Fierce Biotech, 2017-03-24 11:47:03

CountClust – visualizing the structure of RNA-seq expression data using grade of membership models
Grade of membership models, also known as “admixture models”, “topic models” or “Latent Dirichlet Allocation”, are a generalization of cluster models that allow each sample to have membership in multiple clusters. These models are widely used in population genetics to model admixed individuals who have ancestry from multiple “populations”, and in natural language processing to ...
Transcriptome Research & Industry News, 2017-03-24 11:45:18

First Humira biosimilar approved in Europe
Amgen has won European approval for its first biosimilar, a version of AbbVie’s blockbuster Humira (adalimumab).
PharmaTimes, 2017-03-24 10:51:49

MSK scientists discover epigenetic mechanism promoting breast cancer
Researchers from Memorial Sloan Kettering Cancer Center (MSK) have identified, for the first time, an epigenetic mechanism promoting breast cancer.
News Medical Life Sciences, 2017-03-24 10:34:28